28 January 2025
Welcome to Elias Ventre and Quentin Marcou, who join the COMPO team, headed by Drs Benzekry and Ciccolini, as Research Associates.
news from the crcm
28 January 2025
Thanks to the Pancreas-View tool, personalized treatment for pancreatic cancer is becoming a reality. By integrating artificial intelligence and molecular signatures, this tool promises to improve treatment efficacy and patient survival.
28 January 2025
Pancreatic cancer, one of the most aggressive cancers, is at the heart of the COMBAT-PDAC project, supported by Europe and the ANR. The aim is to personalize treatments using innovative models and identify biomarkers to improve patient survival.
28 January 2025
Recent publications by the Modesti team in Nat. Struct. Mol. Biol. and Nucleic Acids Res. reveal new DNA repair mechanisms, highlighting the role of disordered regions of XRCC4/XLF and the impact of Lig3 and Lig4 on cell viability.
28 January 2025
Our research team has nurtured brilliant minds that have contributed to groundbreaking discoveries before embarking on exciting new paths.
28 January 2025
Published in Genes & Development, the Coulon team's study identifies a heterozygous variant of RPA2 as a new cause of disorders in telomere biology, impacting their stability and regulation.
28 January 2025
The MarMaRa Institute, which brings together over 30 interdisciplinary research teams, now welcomes the Telomeres and Chromatin team. This partnership will strengthen research into rare diseases, combining genetics, systems biology and therapeutic innovations to improve diagnosis and treatment.
28 January 2025
SouthROCK is a consortium of excellence dedicated to pediatric cancer research, bringing together 250 experts from Lyon and Marseille. Its multidisciplinary work aims to accelerate scientific advances, improve care and prevent the side effects of treatment for sick children.
28 January 2025
Dr Christophe Ginestier receives a €200,000 Pink Ribbon Award for his project on breast cancer treatment resistance, aimed at identifying new therapies to prevent recurrence.
28 January 2025
Published in Cellular and Molecular Gastroenterology and Hepatology, the De Sepulveda team's study demonstrates that the MAN2A1-FER oncoprotein, present in several cancers, lacks kinase activity, calling into question the efficacy of tyrosine kinase inhibitors as a therapeutic strategy.
28 January 2025
The new ANR-funded project will explore the non-canonical roles of CDK6 and pave the way for innovative leukemia treatments using advanced models and drug repositioning strategies.
28 January 2025
Published in ACS Nano, the study deciphers the impact of biophysical parameters and individual immune response on the efficacy of immune cell engagers, paving the way for optimizing their design in immunotherapy.