Interview with Rima Kochman, doctoral student in the Coulon team
25 November 2024
Preprints and recent submissions from the Modesti team: promising work undergoing validation
3 December 2024
Over a hundred people have come to learn and develop the research carried out by the team. We are sorry to say that it is impossible to list all the people who have worked in our team. In this article, you will find 6 names who have spent part of their Inserm career in the team and have shaped the laboratory's themes.
Initially as a post-doctoral researcher, Béatrice GAUGLER was rapidly recruited to the team as an Inserm CR in 1999, and made a major contribution to the development of the immunomonitoring platform's activities (Mohty et al. 2001). Together with Mohamad MOTHY, Béatrice is the author of a seminal article describing plasmacytoid dendritic cells (pDCs) (Mohty et al. 2003).
After a spell in Besançon, Béatrice GAUGLER-VERJUS joined the Saint-Antoine Research Center in Paris.
Marguerite GHIOTTO helped set up the team in 1985 under the direction of Claude MAWAS, with Daniel OLIVE. Having joined the laboratory as an Inserm technician, Maguy passed the internal competitive examination to become a research engineer. Over the course of her career, she has developed techniques for the generation and characterization of numerous monoclonal antibodies used in immuno-oncology.
She was instrumental in the team's major discoveries concerning the analysis of costimulatory molecules of the immunoglobulin superfamily (IgSF) (Pagès et al. 1994 ; Ghiotto et al. 2010).
Maguy then joined the Marseille-Luminy Immunology Center as head of communications.
Starting out as a post-doctoral researcher, Yves COLLETTE was recruited to the team as an Inserm CR in 1998, then as an Inserm DR in 2007. With his group, he has studied the relationships between viral proteins and T lymphocyte signaling molecules(Bonello et al. 2004).
As part of the team's general work on costimulatory molecules, he focused on members of the TNFSF and TNFRSF superfamily (Castellano et al. 2006).
Yves currently heads one of the CRCM teams.
As a PhD student in the team (2001 - 2005), Cyril FAURIAT studied NK cell biology in a leukemic context with Régis COSTELLO. After returning from post-doctoral training, he was recruited to the team as an Inserm CR in 2011.
He has developed his research work around NK cells in a leukemic context with adapted experimental models (Bou-Tayeh et al. 2021) and provided significant support for immunomonitoring platform activities (Chretien et al. 2021).
Cyril joined another CRCM team.
Ivan HIRSCH trained at the school of Czech virologists recruited by Inserm. He had previously worked on HIV infections at Inserm's U372 unit in Marseille.
After his work on lentiviruses, Ivan joined the team to develop research on flaviviruses, in particular HCV, the hepatitis C virus. Among other things, he described an elegant mechanism of interaction between HCV and plasmacytoid dendritic cells (pDCs) (Florentin et al. 2012).
Following his career at Inserm, he was appointed Professor of Genetics, Molecular Biology and Virology at Charles University in Prague (CZ).
Prior to joining the team, Françoise GONDOIS-REY worked at the Institut Pasteur in Paris, where she was involved in the discovery of the HIV-1 virus (Barré-Sinoussi et al. 1983), then at the Inserm U372 unit in Marseille.
Françoise joined the team after training in multiparametric flow cytometry at the NIH, Bethesda. Over the years, she has made a major contribution to the development of cytometry at our center, both at team and platform level.
The latest work focuses on the dialogue between T lymphocytes and neutrophils (Gondois-Rey et al. 2022)
