{"id":10130,"date":"2025-12-08T15:55:06","date_gmt":"2025-12-08T14:55:06","guid":{"rendered":"https:\/\/crcm-marseille.fr\/?post_type=tribe_events&#038;p=10130"},"modified":"2025-12-09T09:50:11","modified_gmt":"2025-12-09T08:50:11","slug":"russell-rockne","status":"publish","type":"tribe_events","link":"https:\/\/crcm-marseille.fr\/en\/evenement\/russell-rockne\/","title":{"rendered":"Russell Rockne"},"content":{"rendered":"<div  class=\"tribe-events-schedule tribe-clearfix\" >\n\t<p class=\"tribe-events-schedule__datetime\">\n\t\t<span class=\"tribe-events-schedule__date tribe-events-schedule__date--start\">\n\t\t\t18 December, 2025\t\t<\/span>\n\n\t\t\t\t\t<span class=\"tribe-events-schedule__separator tribe-events-schedule__separator--date\">\n\t\t\t\t \/\t\t\t<\/span>\n\t\t\t<span class=\"tribe-events-schedule__time tribe-events-schedule__time--start\">\n\t\t\t\t10h00\t\t\t<\/span>\n\t\t\n\t\t\t\t\t\t\t\t\t<span class=\"tribe-events-schedule__separator tribe-events-schedule__separator--time\">\n\t\t\t\t\t &#8211; \t\t\t\t<\/span>\n\t\t\t\n\t\t\t\t\t\t\t<span class=\"tribe-events-schedule__time tribe-events-schedule__time--end\">\n\t\t\t\t\t11h00\t\t\t\t<\/span>\n\t\t\t\n\t\t\t\t\t\t<\/p>\n<\/div>\n\n\n\n<p><strong>Synopsis<\/strong>: <em>In this talk, I will present how mathematical modeling, developed through close interdisciplinary collaboration with biologists and clinicians, can be used to predict cancer progression and guide therapeutic decision-making. I will share examples from three areas of translational research: CAR T-cell immunotherapy for solid tumors, targeted radionuclide therapy for multiple myeloma, and tyrosine kinase inhibitor therapy for acute myeloid leukemia. Each case study will focus on a specific clinical challenge, the modeling approach used to address it, and how the results have informed or could inform patient care. <\/em><\/p>\n\n\n\n<p><em>The goal is to demonstrate how quantitative frameworks can enhance our understanding of treatment dynamics, resistance mechanisms, and therapeutic optimization. <\/em><\/p>\n\n\n\n<p><em>I will conclude with a forward-looking perspective on integrating artificial intelligence with mechnistic modeling to accelerate the development of personalized cancer therapies.<\/em><\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"724\" height=\"1024\" src=\"https:\/\/crcm-marseille.fr\/wp-content\/uploads\/2025\/12\/Russell-Rockne-Translate-IT-724x1024.jpg\" alt=\"\" class=\"wp-image-10147\" srcset=\"https:\/\/crcm-marseille.fr\/wp-content\/uploads\/2025\/12\/Russell-Rockne-Translate-IT-724x1024.jpg 724w, https:\/\/crcm-marseille.fr\/wp-content\/uploads\/2025\/12\/Russell-Rockne-Translate-IT-212x300.jpg 212w, https:\/\/crcm-marseille.fr\/wp-content\/uploads\/2025\/12\/Russell-Rockne-Translate-IT-53x75.jpg 53w, https:\/\/crcm-marseille.fr\/wp-content\/uploads\/2025\/12\/Russell-Rockne-Translate-IT-480x679.jpg 480w\" sizes=\"auto, (max-width:767px) 480px, 724px\" \/><\/figure>\n\n\n<div  class=\"tribe-block tribe-block__event-price\" >\n\t\t<\/div>\n\n\n<div  class=\"tribe-block tribe-block__venue tribe-clearfix\" >\n\t\n\t\t\n\t<\/div>\n\n\n\n\n\n\n\t<div  class=\"tribe-block tribe-block__events-link\" >\n\t\t<div class=\"tribe-events tribe-common\">\n\t\t\t<div class=\"tribe-events-c-subscribe-dropdown__container\">\n\t\t\t\t<div class=\"tribe-events-c-subscribe-dropdown\">\n\t\t\t\t\t<div class=\"tribe-common-c-btn-border tribe-events-c-subscribe-dropdown__button\">\n\t\t\t\t\t\t<svg\n\t class=\"tribe-common-c-svgicon tribe-common-c-svgicon--cal-export 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tribe-common-c-svgicon--caret-down tribe-events-c-subscribe-dropdown__button-icon\" \taria-hidden=\"true\"\n\tviewBox=\"0 0 10 7\"\n\txmlns=\"http:\/\/www.w3.org\/2000\/svg\"\n>\n\t<path fill-rule=\"evenodd\" clip-rule=\"evenodd\" d=\"M1.008.609L5 4.6 8.992.61l.958.958L5 6.517.05 1.566l.958-.958z\" class=\"tribe-common-c-svgicon__svg-fill\"\/>\n<\/svg>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div id=\"tribe-events-subscribe-dropdown-content\" class=\"tribe-events-c-subscribe-dropdown__content\">\n\t\t\t\t\t\t<ul class=\"tribe-events-c-subscribe-dropdown__list\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<li class=\"tribe-events-c-subscribe-dropdown__list-item 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[\u2026]<\/span><\/p>\n","protected":false},"author":3,"featured_media":10131,"template":"","meta":{"_tec_requires_first_save":false,"_EventAllDay":false,"_EventTimezone":"Europe\/Paris","_EventStartDate":"2025-12-18 10:00:00","_EventEndDate":"2025-12-18 11:00:00","_EventStartDateUTC":"2025-12-18 09:00:00","_EventEndDateUTC":"2025-12-18 10:00:00","_EventShowMap":false,"_EventShowMapLink":false,"_EventURL":"","_EventCost":"","_EventCostDescription":"","_EventCurrencySymbol":"$","_EventCurrencyCode":"USD","_EventCurrencyPosition":"prefix","_EventDateTimeSeparator":" \/","_EventTimeRangeSeparator":" - 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This site is optimized with the Yoast SEO plugin v26.9 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Russell Rockne | CRCM<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/crcm-marseille.fr\/en\/evenement\/russell-rockne\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Russell Rockne | CRCM\" \/>\n<meta property=\"og:description\" content=\"Synopsis: In this talk, I will present how mathematical modeling, developed through close interdisciplinary [\u2026]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/crcm-marseille.fr\/en\/evenement\/russell-rockne\/\" \/>\n<meta property=\"og:site_name\" content=\"CRCM\" \/>\n<meta property=\"article:modified_time\" content=\"2025-12-09T08:50:11+00:00\" \/>\n<meta property=\"og:image\" 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