{"id":6000,"date":"2024-12-03T15:39:41","date_gmt":"2024-12-03T14:39:41","guid":{"rendered":"https:\/\/crcm-marseille.fr\/uncategorized\/preprints-and-recent-submissions-from-the-modesti-team-promising-work-undergoing-validation\/"},"modified":"2025-04-24T11:23:17","modified_gmt":"2025-04-24T09:23:17","slug":"preprints-and-recent-submissions-from-the-modesti-team-promising-work-undergoing-validation","status":"publish","type":"post","link":"https:\/\/crcm-marseille.fr\/en\/modesti-team\/preprints-and-recent-submissions-from-the-modesti-team-promising-work-undergoing-validation\/","title":{"rendered":"Preprints and recent submissions from the Modesti team: promising work undergoing validation"},"content":{"rendered":"\n<p><strong>This work is currently being validated by the scientific community:<\/strong><\/p>\n\n<ul class=\"wp-block-list\">\n<li>Firsanov D, Zacher M, Tian X, Sformo TL, Zhao Y, Tombline G, Lu JY, Zheng Z, Perelli L, Gurreri E, Zhang L, Guo J, Korotkov A, Volobaev V, Biashad SA, Zhang Z, Heid J, Maslov A, Sun S, Wu Z, Gigas J, Hillpot E, Martinez J, Lee M, Williams A, Gilman A, Hamilton N, Haseljic E, Patel A, Straight M, Miller N, Ablaeva J, Tam LM, Couderc C, Hoopman M, Moritz R, Fujii S, Hayman DJ, Liu H, Cai Y, Leung AKL, Simons MJP, Zhang Z, Nelson CB, Abegglen LM, Schiffman JD, Gladyshev VN, Modesti M, Genovese G, Vijg J, Seluanov A, Gorbunova V. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39574710\/\"><strong>DNA repair and anti-cancer mechanisms in the long-lived bowhead whale<\/strong>.<\/a> bioRxiv [Preprint]. 2024 Nov 5:2023.05.07.539748. doi: 10.1101\/2023.05.07.539748.     <\/li>\n<\/ul>\n\n<ul class=\"wp-block-list\">\n<li>Yimeng Zhu, Angelina Li, Suvrajit Maji, Brian J. Lee, Sophie M. Korn, Jake A. Gertie, Tyler J. Dorrity, Jianhua Wang, Kyle J. Wang, Amandine Pelletier, Daniel F. Moakley, Rachel D. Kelly, Antony B. Holmes, Raul Rabadan, David R. Edgell, Caroline Schild Poulter, Mauro Modesti, Anna-Lena Steckelberg, Eric A. Hendrickson, Hachung Chung, Chaolin Zhang, Shan Zha. Ku suppresses RNA-mediated innate immune responses in human cells to accommodate primate-specific Alu expansion. Submitted  <\/li>\n<\/ul>\n\n<ul class=\"wp-block-list\">\n<li>Zhu Y, Lee BJ, Fujii S, Jonchhe S, Zhang H, Li A, Wang KJ, Rothenberg E, Modesti M, Zha S. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39253422\/\"><strong>The KU70-SAP domain has an overlapping function with DNA-PKcs in limiting the lateral movement of KU along DNA<\/strong>.<\/a> bioRxiv [Preprint]. 2024 Aug 27:2024.08.26.609806. <\/li>\n<\/ul>\n\n<ul class=\"wp-block-list\">\n<li>Buehl CJ, Goff NJ, Mikhova M, Hardwick SW, Blundell TL, Modesti M, Schmidt JC, Chaplin A, Meek K. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38168382\/\"><strong>Unravelling the complexities of DNA-PK activation by structure-based mutagenesis<\/strong>.<\/a> Res Sq [Preprint]. 2023 Dec 13:rs.3.rs-3627471. <\/li>\n<\/ul>\n\n<div style=\"height:50px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<div class=\"wp-block-buttons is-content-justification-center is-layout-flex wp-container-core-buttons-is-layout-16018d1d wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/crcm-marseille.fr\/en\/genome-integrity-department\/homologous-recombination-nhej-and-genomic-integrity-team-genome-integrity-department\/\">Find out more about the Modesti team<\/a><\/div>\n<\/div>\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Discover the latest research from the Modesti team, currently being evaluated by the scientific community. These studies explore key mechanisms of DNA repair and cell regulation. <\/p>\n","protected":false},"author":3,"featured_media":5479,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_tec_requires_first_save":true,"_EventAllDay":false,"_EventTimezone":"","_EventStartDate":"","_EventEndDate":"","_EventStartDateUTC":"","_EventEndDateUTC":"","_EventShowMap":false,"_EventShowMapLink":false,"_EventURL":"","_EventCost":"","_EventCostDescription":"","_EventCurrencySymbol":"","_EventCurrencyCode":"","_EventCurrencyPosition":"","_EventDateTimeSeparator":"","_EventTimeRangeSeparator":"","_EventOrganizerID":[],"_EventVenueID":[],"_OrganizerEmail":"","_OrganizerPhone":"","_OrganizerWebsite":"","_VenueAddress":"","_VenueCity":"","_VenueCountry":"","_VenueProvince":"","_VenueState":"","_VenueZip":"","_VenuePhone":"","_VenueURL":"","_VenueStateProvince":"","_VenueLat":"","_VenueLng":"","_VenueShowMap":false,"_VenueShowMapLink":false,"_tribe_blocks_recurrence_rules":"","_tribe_blocks_recurrence_description":"","_tribe_blocks_recurrence_exclusions":"","footnotes":""},"categories":[200,203,213],"tags":[],"class_list":["post-6000","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-genome-integrity-department","category-scientific-publication","category-modesti-team"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.9 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Preprints and recent submissions from the Modesti team: promising work undergoing validation | CRCM<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/crcm-marseille.fr\/en\/modesti-team\/preprints-and-recent-submissions-from-the-modesti-team-promising-work-undergoing-validation\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Preprints and recent submissions from the Modesti team: promising work undergoing validation | CRCM\" \/>\n<meta property=\"og:description\" content=\"Discover the latest research from the Modesti team, currently being evaluated by the scientific community. 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