{"id":10636,"date":"2025-12-22T14:52:30","date_gmt":"2025-12-22T13:52:30","guid":{"rendered":"https:\/\/crcm-marseille.fr\/?p=10636"},"modified":"2025-12-22T16:19:21","modified_gmt":"2025-12-22T15:19:21","slug":"latest-crcm-publications-2","status":"publish","type":"post","link":"https:\/\/crcm-marseille.fr\/en\/crcm-articles\/latest-crcm-publications-2\/","title":{"rendered":"Latest CRCM publications"},"content":{"rendered":"\n<p>Over the past two months, CRCM teams have been engaged in intense scientific activity, as evidenced by numerous publications in leading international journals.<\/p>\n\n\n\n<p>This work demonstrates the diversity of the center&#8217;s expertise, the quality of its collaborations, and the constant commitment of its researchers to advancing our understanding of cancer mechanisms and developing new therapeutic approaches.<\/p>\n\n\n\n<p>Below is a list of all <strong>CRCM scientific publications<\/strong> released during this period.<\/p>\n\n\n\n<div style=\"height:26px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p class=\"has-text-color has-link-color has-medium-font-size wp-elements-7724a3e33d79e145501c7c52e27c4155\" style=\"color:#e9640d\"><strong>OHIO Department<\/strong><\/p>\n\n\n\n<p><strong>Nun\u00e8s \/ Devillier team<\/strong><\/p>\n\n\n\n<i class=\"fa-regular fa-circle-right\" style=\"color:#e9640d;\"><\/i> <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41397201\/\" target=\"_blank\" style=\"text-decoration: underline;\">Factors Associated With Toxicity of FOLFIRINOX in Elderly Patients With Pancreatic Ductal Adenocarcinoma. <\/a><\/br><\/br>\n\n<i class=\"fa-regular fa-circle-right\" style=\"color:#e9640d;\"><\/i> <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41365870\/\" target=\"_blank\" style=\"text-decoration: underline;\">Adaptation of redox metabolism in drug-tolerant persister cells is a vulnerability to prevent relapse in pancreatic cancer. <\/a><\/br><\/br>\n\n<i class=\"fa-regular fa-circle-right\" style=\"color:#e9640d;\"><\/i> <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41255738\/\" target=\"_blank\" style=\"text-decoration: underline;\">Immediate variations in high-dimensional circulating immune cells following pancreatectomy. <\/a><\/br><\/br>\n\n<i class=\"fa-regular fa-circle-right\" style=\"color:#e9640d;\"><\/i> <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41136265\/\" target=\"_blank\" style=\"text-decoration: underline;\">Pathophysiological rationale and management of anxio-depressive syndrome among cancer patients.<\/a><\/br><\/br>\n\n\n\n<p><strong>Chames team<\/strong><\/p>\n\n\n\n<i class=\"fa-regular fa-circle-right\" style=\"color:#e9640d;\"><\/i> <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40801950\/\" target=\"_blank\" style=\"text-decoration: underline;\">Junctional adhesion molecule-C: A multifunctional mediator of cell adhesion.\n<\/a><\/br><\/br>\n\n\n\n<div style=\"height:35px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p class=\"has-text-color has-link-color has-medium-font-size wp-elements-478f961a479971ef643cd718f492b057\" style=\"color:#187fc1\"><strong>Translate-it Department<\/strong><\/p>\n\n\n\n<p><strong>Dusetti \/ Iovanna<\/strong> <strong>team<\/strong><\/p>\n\n\n\n<i class=\"fa-regular fa-circle-right\" style=\"color:#187fc1;\"><\/i> <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41397201\/\" target=\"_blank\" style=\"text-decoration: underline;\">Factors Associated With Toxicity of FOLFIRINOX in Elderly Patients With Pancreatic Ductal Adenocarcinoma. \n<\/a><\/br><\/br>\n\n<i class=\"fa-regular fa-circle-right\" style=\"color:#187fc1;\"><\/i> <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41365870\/\" target=\"_blank\" style=\"text-decoration: underline;\">Adaptation of redox metabolism in drug-tolerant persister cells is a vulnerability to prevent relapse in pancreatic cancer. \n<\/a><\/br><\/br>\n\n<i class=\"fa-regular fa-circle-right\" style=\"color:#187fc1;\"><\/i> <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41349749\/\" target=\"_blank\" style=\"text-decoration: underline;\">Evaluating the therapeutic role of salvianolic acid A on pancreatic cancer cells through interaction with the intrinsically disordered protein NUPR1.\n<\/a><\/br><\/br>\n\n<i class=\"fa-regular fa-circle-right\" style=\"color:#187fc1;\"><\/i> <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41249113\/\" target=\"_blank\" style=\"text-decoration: underline;\">Synergistic antitumor activity of sorafenib and the NUPR1 inhibitor LZX-2-73 in multiple cancer models. \n<\/a><\/br><\/br>\n\n\n\n<p><strong>Benzekry \/ Ciccolini team<\/strong><\/p>\n\n\n\n<i class=\"fa-regular fa-circle-right\" style=\"color:#187fc1;\"><\/i> <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41372707\/\" target=\"_blank\" style=\"text-decoration: underline;\">Predicting the toxicity-efficacy ratio of venetoclax in real-world patients. <\/a><\/br><\/br>\n\n<i class=\"fa-regular fa-circle-right\" style=\"color:#187fc1;\"><\/i> <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41358436\/\" target=\"_blank\" style=\"text-decoration: underline;\">Clinical oncology pharmacy: French current situation of pharmaceutical interventions in production units in 2024.<\/a><\/br><\/br>\n\n\n\n<p><strong>Mamessier \/ Bertucci team<\/strong><\/p>\n\n\n\n<i class=\"fa-regular fa-circle-right\" style=\"color:#187fc1;\"><\/i> <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41350712\/\" target=\"_blank\" style=\"text-decoration: underline;\">The plasma nanoDSF denaturation profiles predict the presence of breast cancer.<\/a><\/br><\/br>\n\n<i class=\"fa-regular fa-circle-right\" style=\"color:#187fc1;\"><\/i> <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41325571\/\" target=\"_blank\" style=\"text-decoration: underline;\">Amivantamab Plus Lazertinib in Atypical EGFR-Mutated Advanced Non-Small Cell Lung Cancer: Results From CHRYSALIS-2.<\/a><\/br><\/br>\n\n\n\n<p><strong>Pasquier \/ Andr\u00e9 team<\/strong><\/p>\n\n\n\n<i class=\"fa-regular fa-circle-right\" style=\"color:#187fc1;\"><\/i> <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41339186\/\" target=\"_blank\" style=\"text-decoration: underline;\">Chemotherapy-free cancer treatment &#8211; not for everyone yet. <\/a><\/br><\/br>\n\n<i class=\"fa-regular fa-circle-right\" style=\"color:#187fc1;\"><\/i> <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41386001\/\" target=\"_blank\" style=\"text-decoration: underline;\">Pharmacokinetic-Based Dose Adjustment of Selumetinib in 2 Young Children With Neurofibroma. <\/a><\/br><\/br>\n\n\n\n<div style=\"height:35px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p class=\"has-text-color has-link-color has-medium-font-size wp-elements-6d5d923d89528c2b752909d98eb1a2e1\" style=\"color:#7a74b1\"><strong>Genome integrity department<\/strong><\/p>\n\n\n\n<p><strong>Lachaud team<\/strong><\/p>\n\n\n\n<i class=\"fa-regular fa-circle-right\" style=\"color:#7A74B1;\"><\/i> <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41317890\/\" target=\"_blank\" style=\"text-decoration: underline;\">Alkyne modification of DNA cross-linking antitumor agent SJG-136 to monitor induced lesions in cells by click chemistry. <\/a><\/br><\/br>\n\n\n\n<p><strong>Coulon team<\/strong><\/p>\n\n\n\n<i class=\"fa-regular fa-circle-right\" style=\"color:#7A74B1;\"><\/i> <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41248173\/\" target=\"_blank\" style=\"text-decoration: underline;\">Tel1 is recruited at chromosomal loop\/axis contact sites to modulate meiotic DNA double-strand breaks interference.\n<\/a><\/br><\/br>\n\n\n\n<p><strong>Llorente team<\/strong><\/p>\n\n\n\n<i class=\"fa-regular fa-circle-right\" style=\"color:#7A74B1;\"><\/i> <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41248173\/\" target=\"_blank\" style=\"text-decoration: underline;\">Tel1 is recruited at chromosomal loop\/axis contact sites to modulate meiotic DNA double-strand breaks interference. \n<\/a><\/br><\/br>\n\n\n\n<div style=\"height:35px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p class=\"has-text-color has-link-color has-medium-font-size wp-elements-b6f993e611a74cf46e9dd54680d34fd5\" style=\"color:#5dbdad\"><strong>COMET Department<\/strong><\/p>\n\n\n\n<p><strong>Vasseur \/ Tomasini team<\/strong><\/p>\n\n\n\n<i class=\"fa-regular fa-circle-right\" style=\"color:#5dbdad;\"><\/i> <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41385622\/\" target=\"_blank\" style=\"text-decoration: underline;\">The extracellular matrix drives guanylate production and protects pancreatic cancer cells from oxaliplatin-induced DNA damage. <\/a><\/br><\/br>\n\n\n\n<p><strong>Borg \/ Maina team<\/strong><\/p>\n\n\n\n<i class=\"fa-regular fa-circle-right\" style=\"color:#5dbdad;\"><\/i> <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41202504\/\" target=\"_blank\" style=\"text-decoration: underline;\">MOVIE phase II trial of tremelimumab plus durvalumab combined with metronomic oral vinorelbine in patients with head and neck cancer. <\/a><\/br><\/br>\n\n\n\n<p><strong>Charafe \/ Ginestier<\/strong> <strong>team<\/strong><\/p>\n\n\n\n<i class=\"fa-regular fa-circle-right\" style=\"color:#5dbdad;\"><\/i> <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41236926\/\" target=\"_blank\" style=\"text-decoration: underline;\">Injury and inflammation promote cancer progression at the anorectal junction. <\/a><\/br><\/br>\n\n\n\n<div style=\"height:63px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Over the past two months, CRCM teams have been engaged in intense scientific activity,<span class=\"excerpt-hellip\"> [\u2026]<\/span><\/p>\n","protected":false},"author":1,"featured_media":10669,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_tec_requires_first_save":true,"_EventAllDay":false,"_EventTimezone":"","_EventStartDate":"","_EventEndDate":"","_EventStartDateUTC":"","_EventEndDateUTC":"","_EventShowMap":false,"_EventShowMapLink":false,"_EventURL":"","_EventCost":"","_EventCostDescription":"","_EventCurrencySymbol":"","_EventCurrencyCode":"","_EventCurrencyPosition":"","_EventDateTimeSeparator":"","_EventTimeRangeSeparator":"","_EventOrganizerID":[],"_EventVenueID":[],"_OrganizerEmail":"","_OrganizerPhone":"","_OrganizerWebsite":"","_VenueAddress":"","_VenueCity":"","_VenueCountry":"","_VenueProvince":"","_VenueState":"","_VenueZip":"","_VenuePhone":"","_VenueURL":"","_VenueStateProvince":"","_VenueLat":"","_VenueLng":"","_VenueShowMap":false,"_VenueShowMapLink":false,"_tribe_blocks_recurrence_rules":"","_tribe_blocks_recurrence_description":"","_tribe_blocks_recurrence_exclusions":"","footnotes":""},"categories":[231,196,197,202,205,206,207,209,210,214,226,228,230],"tags":[],"class_list":["post-10636","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-team-vasseur-tomasini","category-benzekry-ciccolini-team","category-team-dusetti-iovanna","category-team-chames","category-crcm-articles","category-team-charafe-ginestier","category-the-coulon-team","category-bertucci-mamessier-team","category-team-pasquier-andre","category-team-borg-maina","category-team-lachaud","category-nunes-devillier-team","category-team-llorente"],"yoast_head":"<!-- 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