{"id":5947,"date":"2025-01-07T11:17:14","date_gmt":"2025-01-07T10:17:14","guid":{"rendered":"https:\/\/crcm-marseille.fr\/our-technology-platforms\/smartc-platform\/"},"modified":"2025-11-18T10:41:06","modified_gmt":"2025-11-18T09:41:06","slug":"smartc","status":"publish","type":"page","link":"https:\/\/crcm-marseille.fr\/en\/our-technology-platforms\/smartc\/","title":{"rendered":"SMARTc"},"content":{"rendered":"\n<figure class=\"wp-block-image\"><a href=\"https:\/\/crcm-marseille.fr\/en\/\"><img decoding=\"async\" src=\"https:\/\/crcm-marseille.fr\/wp-content\/uploads\/2024\/10\/logo-centre-de-recherche-en-cancerologie-de-marseille-crcm.webp#847\" alt=\"logo-crcm\"\/><\/a><\/figure>\n\n\n\n<ul id=\"menu-main-menu\" class=\"wp-block-list\">\n<li><a href=\"https:\/\/crcm-marseille.fr\/en\/\">Home<\/a><\/li>\n\n\n\n<li><a>Our center<\/a><\/li>\n\n\n\n<li><a>Our research<\/a><\/li>\n\n\n\n<li><a>For students<\/a><\/li>\n\n\n\n<li><a>For scientists<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/crcm-marseille.fr\/our-research-teams\/\">The research teams<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/crcm-marseille.fr\/en\/our-technology-platforms\/smartc\/#\"><\/a><\/li>\n<\/ul>\n\n\n\n<figure class=\"wp-block-image\"><img decoding=\"async\" src=\"https:\/\/crcm-marseille.fr\/wp-content\/plugins\/sitepress-multilingual-cms\/res\/flags\/en.svg\" alt=\"English\"\/><\/figure>\n\n\n\n<h1 class=\"wp-block-heading\">SMARTc<\/h1>\n\n\n\n<p>La Timone<\/p>\n\n\n\n<figure class=\"wp-block-image\"><a class=\" mfn-coverimg-wrapper\" href=\"https:\/\/crcm-marseille.fr\/team\/veronique-chevrier\/\"><img decoding=\"async\" src=\"https:\/\/crcm-marseille.fr\/wp-content\/uploads\/2025\/01\/ciccolini_joseph_crcm-1.jpg\" alt=\"\"\/><\/a><\/figure>\n\n\n\n<p><a href=\"https:\/\/crcm-marseille.fr\/team\/joseph-ciccolini\/\">Joseph Ciccolini<\/a><\/p>\n\n\n\n<p>Platform manager<\/p>\n\n\n\n<p><a href=\"https:\/\/crcm-marseille.fr\/team\/anne-rodallec\/\"><\/a><\/p>\n\n\n\n<figure class=\"wp-block-image\"><a class=\"sptp-member-avatar \" href=\"https:\/\/crcm-marseille.fr\/en\/team\/anne-rodallec\/\"><img decoding=\"async\" src=\"https:\/\/crcm-marseille.fr\/wp-content\/uploads\/2025\/01\/rodallec_anne_crcm-1.jpg\" alt=\"Rodallec Anne COMPO: Pharmacologie COMPutationnelle et Oncologie clinique - CRCM\"\/><\/a><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">Anne Rodallec<\/h2>\n\n\n\n<h4 class=\"wp-block-heading\">Enseignante-Chercheuse<\/h4>\n\n\n\n<p><a href=\"https:\/\/crcm-marseille.fr\/team\/raphaelle-fanciullino\/\"><\/a><\/p>\n\n\n\n<figure class=\"wp-block-image\"><a class=\"sptp-member-avatar \" href=\"https:\/\/crcm-marseille.fr\/en\/team\/raphaelle-fanciullino\/\"><img decoding=\"async\" src=\"https:\/\/crcm-marseille.fr\/wp-content\/uploads\/2025\/01\/fanciullin_raphaelle_crcm.jpg\" alt=\"Fabciullino Raphaelle - Centre de recherche en canc\u00e9rologie de Marseille - Plateforme SMARTc: Mod\u00e9lisation des th\u00e9rapies anticanc\u00e9reuses pour une r\u00e9ponse adaptative\"\/><\/a><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">Rapha\u00eblle Fanciullino<\/h2>\n\n\n\n<h4 class=\"wp-block-heading\">Enseignante-Chercheuse-Praticienne Hospitali\u00e8re<\/h4>\n\n\n\n<p><a href=\"https:\/\/crcm-marseille.fr\/team\/sarah-giacometti\/\"><\/a><\/p>\n\n\n\n<figure class=\"wp-block-image\"><a class=\"sptp-member-avatar \" href=\"https:\/\/crcm-marseille.fr\/en\/team\/sarah-giacometti\/\"><img decoding=\"async\" src=\"https:\/\/crcm-marseille.fr\/wp-content\/uploads\/2025\/01\/giacometti_sarah_crcm2.jpg\" alt=\"Giacometti sarah \u00e9quipe COMPO - Centre de recherche en canc\u00e9rologie de Marseille\"\/><\/a><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">Sarah Giacometti<\/h2>\n\n\n\n<h4 class=\"wp-block-heading\">Technicienne<\/h4>\n\n\n\n<p><a href=\"https:\/\/crcm-marseille.fr\/team\/anne-rodallec\/\"><\/a><\/p>\n\n\n\n<figure class=\"wp-block-image\"><a class=\"sptp-member-avatar \" href=\"https:\/\/crcm-marseille.fr\/en\/team\/anne-rodallec\/\"><img decoding=\"async\" src=\"https:\/\/crcm-marseille.fr\/wp-content\/uploads\/2025\/01\/rodallec_anne_crcm-1.jpg\" alt=\"Rodallec Anne COMPO: Pharmacologie COMPutationnelle et Oncologie clinique - CRCM\"\/><\/a><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">Anne Rodallec<\/h2>\n\n\n\n<h4 class=\"wp-block-heading\">Enseignante-Chercheuse<\/h4>\n\n\n\n<p><a href=\"https:\/\/crcm-marseille.fr\/team\/raphaelle-fanciullino\/\"><\/a><\/p>\n\n\n\n<figure class=\"wp-block-image\"><a class=\"sptp-member-avatar \" href=\"https:\/\/crcm-marseille.fr\/en\/team\/raphaelle-fanciullino\/\"><img decoding=\"async\" src=\"https:\/\/crcm-marseille.fr\/wp-content\/uploads\/2025\/01\/fanciullin_raphaelle_crcm.jpg\" alt=\"Fabciullino Raphaelle - Centre de recherche en canc\u00e9rologie de Marseille - Plateforme SMARTc: Mod\u00e9lisation des th\u00e9rapies anticanc\u00e9reuses pour une r\u00e9ponse adaptative\"\/><\/a><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">Rapha\u00eblle Fanciullino<\/h2>\n\n\n\n<h4 class=\"wp-block-heading\">Enseignante-Chercheuse-Praticienne Hospitali\u00e8re<\/h4>\n\n\n\n<p><a href=\"https:\/\/crcm-marseille.fr\/team\/sarah-giacometti\/\"><\/a><\/p>\n\n\n\n<figure class=\"wp-block-image\"><a class=\"sptp-member-avatar \" href=\"https:\/\/crcm-marseille.fr\/en\/team\/sarah-giacometti\/\"><img decoding=\"async\" src=\"https:\/\/crcm-marseille.fr\/wp-content\/uploads\/2025\/01\/giacometti_sarah_crcm2.jpg\" alt=\"Giacometti sarah \u00e9quipe COMPO - Centre de recherche en canc\u00e9rologie de Marseille\"\/><\/a><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">Sarah Giacometti<\/h2>\n\n\n\n<h4 class=\"wp-block-heading\">Technicienne<\/h4>\n\n\n\n<p><a href=\"https:\/\/crcm-marseille.fr\/team\/anne-rodallec\/\"><\/a><\/p>\n\n\n\n<figure class=\"wp-block-image\"><a class=\"sptp-member-avatar \" href=\"https:\/\/crcm-marseille.fr\/en\/team\/anne-rodallec\/\"><img decoding=\"async\" src=\"https:\/\/crcm-marseille.fr\/wp-content\/uploads\/2025\/01\/rodallec_anne_crcm-1.jpg\" alt=\"Rodallec Anne COMPO: Pharmacologie COMPutationnelle et Oncologie clinique - CRCM\"\/><\/a><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">Anne Rodallec<\/h2>\n\n\n\n<h4 class=\"wp-block-heading\">Enseignante-Chercheuse<\/h4>\n\n\n\n<p><a href=\"https:\/\/crcm-marseille.fr\/team\/raphaelle-fanciullino\/\"><\/a><\/p>\n\n\n\n<figure class=\"wp-block-image\"><a class=\"sptp-member-avatar \" href=\"https:\/\/crcm-marseille.fr\/en\/team\/raphaelle-fanciullino\/\"><img decoding=\"async\" src=\"https:\/\/crcm-marseille.fr\/wp-content\/uploads\/2025\/01\/fanciullin_raphaelle_crcm.jpg\" alt=\"Fabciullino Raphaelle - Centre de recherche en canc\u00e9rologie de Marseille - Plateforme SMARTc: Mod\u00e9lisation des th\u00e9rapies anticanc\u00e9reuses pour une r\u00e9ponse adaptative\"\/><\/a><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">Rapha\u00eblle Fanciullino<\/h2>\n\n\n\n<h4 class=\"wp-block-heading\">Enseignante-Chercheuse-Praticienne Hospitali\u00e8re<\/h4>\n\n\n\n<p><a href=\"https:\/\/crcm-marseille.fr\/team\/sarah-giacometti\/\"><\/a><\/p>\n\n\n\n<figure class=\"wp-block-image\"><a class=\"sptp-member-avatar \" href=\"https:\/\/crcm-marseille.fr\/en\/team\/sarah-giacometti\/\"><img decoding=\"async\" src=\"https:\/\/crcm-marseille.fr\/wp-content\/uploads\/2025\/01\/giacometti_sarah_crcm2.jpg\" alt=\"Giacometti sarah \u00e9quipe COMPO - Centre de recherche en canc\u00e9rologie de Marseille\"\/><\/a><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">Sarah Giacometti<\/h2>\n\n\n\n<h4 class=\"wp-block-heading\">Technicienne<\/h4>\n\n\n\n<p>The SMARTc platform specializes in optimizing&nbsp;the efficacy\/toxicity balance of anti-cancer drugs in clinical and preclinical settings, through pharmacokinetic optimization. Several strategies are implemented, such as pharmacogenetic studies, the use of mathematical models to define the administration and\/or combination modalities of therapies, or the synthesis of nanomedicines enabling better targeting and longer residence in the body.<\/p>\n\n\n\n<p>The SMARTc platform, located on the Timone Health Campus (Faculty of Pharmacy and Timone University Hospital),&nbsp;<strong>The aim is to optimize the efficacy\/toxicity balance of anti-cancer drugs.<\/strong>&nbsp;SMARTc is built around a group of pharmacists and modelers, working with pharmacological and clinical researchers in a laboratory equipped and approved by veterinary services to conduct experimental studies (in vitro, in vivo) with&nbsp;<strong>a strong specialization in drug pharmacokinetics.<\/strong><br>SMARTc is also supported by the APHM Biogenop\u00f4le, a platform for the bioanalytical assay of anti-cancer drugs (small molecules, biotherapies, ADCs) and their metabolites in an ISO15189-certified environment. This expertise covers the full range of treatments, from cytotoxic chemotherapy to oral targeted therapies and biologics, including immunotherapy products, at both preclinical and clinical development stages.<\/p>\n\n\n\n<p>This includes:<\/p>\n\n\n\n<p>&#8211;&nbsp;Develop&nbsp;dose adjustment algorithms including biomarkers of interest.<br>&#8211;&nbsp;Identify&nbsp;genetic or phenotypic covariates impacting drug PK\/PD relationships.<br>&#8211;&nbsp;Develop&nbsp;new combination treatment protocols optimized by PK\/PD modeling<br>&#8211;&nbsp;Developing&nbsp;metronomic strategies optimized by PK\/PD modeling<br>&#8211;&nbsp;Developing&nbsp;nanoparticles optimized by PK\/PD modeling<br>&#8211;&nbsp;Develop&nbsp;tools to optimize combinations of immunotherapy and associated treatments.<br>&#8211;&nbsp;Develop&nbsp;tools for better clinical trial design, particularly in the early phases.<br>&#8211;&nbsp;Conduct&nbsp;pharmacokinetic analysis and biodistribution studies on small rodents<br>&#8211;&nbsp;Carry out&nbsp;pharmacokinetic analysis in phase I and phase I\/II clinical trials in an Iso15189 environment.<\/p>\n\n\n\n<figure class=\"wp-block-image\"><img decoding=\"async\" src=\"https:\/\/crcm-marseille.fr\/wp-content\/uploads\/2025\/02\/SMARTc-plateforme.jpg\" alt=\"\"\/><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">PROJECTS TO WHICH THE PLATFORM CONTRIBUTES<\/h2>\n\n\n\n<p>Thermonano<\/p>\n\n\n\n<p>PIONEER<\/p>\n\n\n\n<p>MOIO<\/p>\n\n\n\n<p>NANOIMMUNO<\/p>\n\n\n\n<figure class=\"wp-block-image\"><img decoding=\"async\" src=\"https:\/\/crcm-marseille.fr\/wp-content\/uploads\/2024\/12\/forme-orange-plateforme-left-crcm.png\" alt=\"\"\/><\/figure>\n\n\n\n<figure class=\"wp-block-image\"><img decoding=\"async\" src=\"https:\/\/crcm-marseille.fr\/wp-content\/uploads\/2024\/12\/forme-orange-plateforme-right-crcm.png\" alt=\"\"\/><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">front-page publications<\/h2>\n\n\n\n<p>02\/2025<\/p>\n\n\n\n<p><a href=\"https:\/\/doi.org\/10.1111\/fcp.13049\" target=\"_blank\" rel=\"noreferrer noopener\">Body mass index affects imatinib exposure: Real-world evidence from TDM with adaptive dosing. Fundam Clin Pharmacol.<\/a><\/p>\n\n\n\n<p>Maroselli P, Fanciullino R, Colle J, Farnault L, Roche P, Venton G, Costello R, Ciccolini J.<\/p>\n\n\n\n<p>11\/2024<\/p>\n\n\n\n<p><a href=\"https:\/\/doi.org\/10.1111\/bcp.16343\" target=\"_blank\" rel=\"noreferrer noopener\">Adaptive dosing of high-dose busulfan in real-world adult patients undergoing haematopoietic cell transplant conditioning. Br J Clin Pharmacol.<\/a><\/p>\n\n\n\n<p>Protzenko D, Bouchacourt B, Carriat L, Maroselli P, Bo\u00e9ri C, Devillier R, Ciccolini J.<\/p>\n\n\n\n<p>11\/2023<\/p>\n\n\n\n<p><a href=\"https:\/\/doi.org\/10.1002\/psp4.13063\" target=\"_blank\" rel=\"noreferrer noopener\">Killing a fly with a sledgehammer: Atezolizumab exposure in real-world lung cancer patients. CPT Pharmacometrics Syst Pharmacol.<\/a><\/p>\n\n\n\n<p>Marolleau S, Mogenet A, Boeri C, Hamimed M, Ciccolini J, Greillier L.<\/p>\n\n\n\n<p>11\/2023<\/p>\n\n\n\n<p><a href=\"https:\/\/doi.org\/10.1111\/bjh.19096\" target=\"_blank\" rel=\"noreferrer noopener\">Cytidine deaminase status as a marker of response to azacytidine treatment in MDS and AML patients. Br J Haematol.<\/a><\/p>\n\n\n\n<p>Donnette M, Hamimed M, Ciccolini J, Sicard G, Correard F, Farnault L, Ouafik L, Venton G, Fanciullino R.<\/p>\n\n\n\n<p>10\/2023<\/p>\n\n\n\n<p><a href=\"https:\/\/doi.org\/10.1038\/s41416-023-02350-7\" target=\"_blank\" rel=\"noreferrer noopener\">Harnessing tumor immunity with cytotoxics: T cells monitoring in mice bearing lung tumors treated with anti-VEGF and pemetrexed-cisplatin doublet. Br J Cancer.<\/a><\/p>\n\n\n\n<p>Sicard G, Protzenko D, Giacometti S, Barl\u00e9si F, Ciccolini J, Fanciullino R.<\/p>\n\n\n\n<p>05\/2023<\/p>\n\n\n\n<p><a href=\"https:\/\/bmccancer.biomedcentral.com\/articles\/10.1186\/s12885-023-10881-8\" target=\"_blank\" rel=\"noreferrer noopener\">A non-inferiority randomized phase III trial of standard immunotherapy by checkpoint inhibitors vs. reduced dose intensity in responding patients with metastatic cancer: the MOIO protocol study. BMC Cancer.<\/a><\/p>\n\n\n\n<p>Gravis G, Marino P, Olive D, Penault-LLorca F, Delord JP, Simon C, Lamrani-Ghaouti A, Sabatier R, Ciccolini J, Boher JM.<\/p>\n\n\n\n<p><a href=\"https:\/\/crcm-marseille.fr\/wp-content\/uploads\/2025\/01\/SMARTc_publications.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">All our publications<\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Labels, Funding and Partners<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li><a href=\"https:\/\/www.univ-amu.fr\/fr\/public\/vers-plus-dexcellence\" target=\"_blank\" rel=\"noreferrer noopener\"><\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/www.merck.com\/\" target=\"_blank\" rel=\"noreferrer noopener\"><\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/www.sydney.edu.au\/\" target=\"_blank\" rel=\"noreferrer noopener\"><\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/www.universite-paris-saclay.fr\/\" target=\"_blank\" rel=\"noreferrer noopener\"><\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/www.roche.fr\/innovation\/institut-roche\" target=\"_blank\" rel=\"noreferrer noopener\"><\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/www.univ-amu.fr\/fr\/public\/vers-plus-dexcellence\" target=\"_blank\" rel=\"noreferrer noopener\"><\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/www.merck.com\/\" target=\"_blank\" rel=\"noreferrer noopener\"><\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/www.sydney.edu.au\/\" target=\"_blank\" rel=\"noreferrer noopener\"><\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/www.universite-paris-saclay.fr\/\" target=\"_blank\" rel=\"noreferrer noopener\"><\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/www.roche.fr\/innovation\/institut-roche\" target=\"_blank\" rel=\"noreferrer noopener\"><\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/www.univ-amu.fr\/fr\/public\/vers-plus-dexcellence\" target=\"_blank\" rel=\"noreferrer noopener\"><\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/www.merck.com\/\" target=\"_blank\" rel=\"noreferrer noopener\"><\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/www.sydney.edu.au\/\" target=\"_blank\" rel=\"noreferrer noopener\"><\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/www.universite-paris-saclay.fr\/\" target=\"_blank\" rel=\"noreferrer noopener\"><\/a><\/li>\n<\/ul>\n\n\n\n<p>Alumni<\/p>\n\n\n\n<p>Like others, they were part of the team.<br>Thank you to all those who have contributed to CRCM&#8217;s excellence and impact.<\/p>\n\n\n\n<figure class=\"wp-block-image\"><img decoding=\"async\" src=\"https:\/\/crcm-marseille.fr\/wp-content\/uploads\/2025\/01\/perez_carla_crcm.jpg\" alt=\"\"\/><\/figure>\n\n\n\n<h5 class=\"wp-block-heading\">Carla Perez<\/h5>\n\n\n\n<h5 class=\"wp-block-heading\">Engineer<br>Currently studying pharmacy, Marseille<\/h5>\n\n\n\n<figure class=\"wp-block-image\"><img decoding=\"async\" src=\"https:\/\/crcm-marseille.fr\/wp-content\/uploads\/2025\/01\/marin_clemence_crcm.jpg\" alt=\"\"\/><\/figure>\n\n\n\n<h5 class=\"wp-block-heading\">Clemence Marin<\/h5>\n\n\n\n<h5 class=\"wp-block-heading\">Doctoral student (intern)<br>Currently biologist, La Piti\u00e9 Salp\u00e9tri\u00e8re Hospital<\/h5>\n\n\n\n<figure class=\"wp-block-image\"><img decoding=\"async\" src=\"https:\/\/crcm-marseille.fr\/wp-content\/uploads\/2025\/01\/marolleau_sophie_crcm.jpg\" alt=\"\"\/><\/figure>\n\n\n\n<h5 class=\"wp-block-heading\">Sophie Marolleau<\/h5>\n\n\n\n<h5 class=\"wp-block-heading\">Engineer<br>Currently a doctoral student, Universit\u00e9 de Poitiers<\/h5>\n\n\n\n<figure class=\"wp-block-image\"><img decoding=\"async\" src=\"https:\/\/crcm-marseille.fr\/wp-content\/uploads\/2025\/02\/serdjebi_cindy_crcm.jpg\" alt=\"\"\/><\/figure>\n\n\n\n<h5 class=\"wp-block-heading\">Cindy Serdjebi<\/h5>\n\n\n\n<h5 class=\"wp-block-heading\">PhD student (FRM grant)<br>Biocellvia Research Director<\/h5>\n\n\n\n<figure class=\"wp-block-image\"><img decoding=\"async\" src=\"https:\/\/crcm-marseille.fr\/wp-content\/uploads\/2025\/01\/hamimed_mourad_crcm.jpg\" alt=\"\"\/><\/figure>\n\n\n\n<h5 class=\"wp-block-heading\">Mourad Hamimed<\/h5>\n\n\n\n<h5 class=\"wp-block-heading\">Doctoral student<br>Currently associate director, CERTARA<\/h5>\n\n\n\n<figure class=\"wp-block-image\"><img decoding=\"async\" src=\"https:\/\/crcm-marseille.fr\/wp-content\/uploads\/2025\/01\/cuplov_vesna_crcm.jpg\" alt=\"\"\/><\/figure>\n\n\n\n<h5 class=\"wp-block-heading\">Vesna Cuplov<\/h5>\n\n\n\n<h5 class=\"wp-block-heading\">Post-doctoral fellow<br>Currently research associate, Institut Curie<\/h5>\n\n\n\n<figure class=\"wp-block-image\"><img decoding=\"async\" src=\"https:\/\/crcm-marseille.fr\/wp-content\/uploads\/2025\/01\/summer_ilyssa_crcm.jpg\" alt=\"\"\/><\/figure>\n\n\n\n<h5 class=\"wp-block-heading\">Ilyssa Summer<\/h5>\n\n\n\n<h5 class=\"wp-block-heading\">Post-doc<br>Currently data scientist, CarePredict, Inc.<\/h5>\n\n\n\n<figure class=\"wp-block-image\"><img decoding=\"async\" src=\"https:\/\/crcm-marseille.fr\/wp-content\/uploads\/2025\/01\/imbs_diane_charlotte_crcm.jpg\" alt=\"\"\/><\/figure>\n\n\n\n<h5 class=\"wp-block-heading\">Diane-Charlotte Imbs<\/h5>\n\n\n\n<h5 class=\"wp-block-heading\">Post-doctoral fellow<br>Currently Clinical Associate Director CERTARA<\/h5>\n\n\n\n<figure class=\"wp-block-image\"><img decoding=\"async\" src=\"https:\/\/crcm-marseille.fr\/wp-content\/uploads\/2025\/01\/el_cheik_raouf_crcm.jpg\" alt=\"\"\/><\/figure>\n\n\n\n<h5 class=\"wp-block-heading\">Raouf El Cheik<\/h5>\n\n\n\n<h5 class=\"wp-block-heading\">Post-doctoral<br>Currently senior manager advanced pharmacometrics,<br>Daiichi Sankyo Oncology France<\/h5>\n\n\n\n<figure class=\"wp-block-image\"><img decoding=\"async\" src=\"https:\/\/crcm-marseille.fr\/wp-content\/uploads\/2025\/01\/sicard_guillaume_crcm.jpg\" alt=\"\"\/><\/figure>\n\n\n\n<h5 class=\"wp-block-heading\">Guillaume Sicard<\/h5>\n\n\n\n<h5 class=\"wp-block-heading\">Doctoral student (Intern APHM)<br>Assistant Hospitalier APHM<\/h5>\n\n\n\n<p><a href=\"https:\/\/intra-crcm.marseille.inserm.fr\/\" target=\"_blank\" rel=\"noreferrer noopener\">Intranet connection<\/a><br><a href=\"https:\/\/crcm-marseille.fr\/annuaire\/\">Directory<\/a><br><a href=\"https:\/\/www.institutpaolicalmettes.fr\/\" target=\"_blank\" rel=\"noreferrer noopener\">IPC collaboration<\/a><br><a href=\"https:\/\/crcm-marseille.fr\/actualites\/\">News<\/a><br><a href=\"https:\/\/crcm-marseille.fr\/evenements\/\">Events<\/a><br><a href=\"https:\/\/crcm-marseille.fr\/en\/our-center\/partnerships-and-innovation\/\">Partnerships &amp; Innovation<\/a><br><a href=\"https:\/\/crcm-marseille.fr\/en\/terms-of-use\/\">Terms &amp; Conditions<\/a><br><a href=\"https:\/\/crcm-marseille.fr\/politique-de-confidentialite\/\">Privacy policy<\/a><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Marseille Cancer Research Center<\/h3>\n\n\n\n<p>27 Bd Le\u00ef Roure, CS 30059<br>13273 Marseille Cedex 09<\/p>\n\n\n\n<p>Tel: 04 86 97 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[\u2026]<\/span><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":5925,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_tec_requires_first_save":true,"_EventAllDay":false,"_EventTimezone":"","_EventStartDate":"","_EventEndDate":"","_EventStartDateUTC":"","_EventEndDateUTC":"","_EventShowMap":false,"_EventShowMapLink":false,"_EventURL":"","_EventCost":"","_EventCostDescription":"","_EventCurrencySymbol":"","_EventCurrencyCode":"","_EventCurrencyPosition":"","_EventDateTimeSeparator":"","_EventTimeRangeSeparator":"","_EventOrganizerID":[],"_EventVenueID":[],"_OrganizerEmail":"","_OrganizerPhone":"","_OrganizerWebsite":"","_VenueAddress":"","_VenueCity":"","_VenueCountry":"","_VenueProvince":"","_VenueState":"","_VenueZip":"","_VenuePhone":"","_VenueURL":"","_VenueStateProvince":"","_VenueLat":"","_VenueLng":"","_VenueShowMap":false,"_VenueShowMapLink":false,"_tribe_blocks_recurrence_rules":"","_tribe_blocks_recurrence_description":"","_tribe_blocks_recurrence_exclusions":"","footnotes":""},"class_list":["post-5947","page","type-page","status-publish","hentry"],"yoast_head":"<!-- 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